Platelets and Megakaryocytes Volume 2 Perspectives and Techniques

Biology and Genetics

Jonathan M. Gibbins, Martyn P. Mahaut-Smith – Platelets and Megakaryocytes: Volume 2: Perspectives and Techniques
John Montgomery, David Bodznick – Evolution of the cerebellar sense of self
Frozen Worlds (DK Readers Level 1) by Caryn Jenner
Blowfish’s Oceanopedia: 291 Extraordinary Things You Didn’t Know About the Sea by Tom ‘The Blowfish’ Hird
Birdmania: A Remarkable Passion for Birds by Bernd Brunner

Jonathan M. Gibbins, Martyn P. Mahaut-Smith – Platelets and Megakaryocytes: Volume 2: Perspectives and Techniques

Published: 2004-08-13 | ISBN: 1588290115, 1617373052 | PDF | 504 pages | 6.26 MB

Platelets are an essential element of the body’s hemostasis system, and yet, through their involvement in thrombosis, are also a major cause of morbidity and mortality. Platelets have a limited lifespan and must be continually manufactured by their precursor, the megakaryocyte. In Platelets and Megakaryocytes, Volume 2: Perspectives and Techniques leading expert researchers-many responsible for seminal discoveries in the field-offer basic and advanced techniques for studying cell signaling in the regulation and function of platelets and megakaryocytes, as well as state-of-the-art commentaries on our understanding of these cells. The methods include ligand-binding assays, the study of protein and lipid kinases and phosphatases, the analysis of lipid rafts in the regulation of cell signaling, and the measurement of intracellular calcium levels. There are also techniques for the study of electrophysiological events, nitric oxide signaling, venom proteins, and for the internalization of proteins into platelets through permeabilization. The application of many molecular and post-genomic methods to the study of platelets and megakaryocytes is also described. All protocols follow the successful Methods in Molecular Biology series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. A companion volume, Platelets and Megakaryocytes, Volume 1: Functional Assays describes in step-by-step detail basic and advanced techniques for analyzing platelet and megakaryocyte function.
Comprehensive and cutting-edge, the two volumes of Platelets and Megakaryocytes offer novice and experienced cell biologists, hematologists, and clinicians not only a benchmark survey of the field, but also a comprehensive library of proven techniques essential for productive research on platelets and megakaryocytes today.

John Montgomery, David Bodznick – Evolution of the cerebellar sense of self

Published: 2017-01-24 | ISBN: 0198758863 | PDF | 224 pages | 106.31 MB

The cerebellum is an intriguing component of the brain. In humans it occupies only 10% of the brain volume, yet has approximately 69 billion neurons; that is 80% of the nerve cells in the brain. The cerebellum first arose in jawed vertebrates such as sharks, and sharks in fact have an additional cerebellum-like structure that works as an adaptive filter. The function of shark cerebellum-like structures is to discriminate ‘self’ from ‘other’ in sensory inputs. With the evolution of the true cerebellum the adaptive filter functionality was adopted for motor control and paved the way for athleticism and movement finesse that we see in swimming, running, climbing and flying vertebrates.
This book uses an evolutionary perspective to open up the exciting body of work that is cerebellar research to a wide audience. Understanding the brain is of interest to many people, from many different backgrounds, and for many different reasons. Therefore, understanding cerebellum is a significant step towards the wider challenge of understanding the brain.
This book wil be of interest to neuroscientists, neurologists and psychologists, in addition to computer scientists, and engineers concerned with machine/human interactions and robotics.

Frozen Worlds (DK Readers Level 1) by Caryn Jenner

English | November 2nd, 2017 | ISBN: 0241285046, 978-0241285046 | 26 Pages | True PDF | 5.92 MB

Explore the coldest places on earth. Discover life in the Antarctic, how Arctic people get around and where polar bears live with DK Reader Frozen Worlds.
DK’s innovative range of levelled readers combines a highly visual approach with non-fiction narratives that children will love reading. DK Reader Frozen Worlds is a level 1 reader, Learning to Read, offering a delightful narrative for young children to encourage an interest in and desire to read. Simple sentences are used with an emphasis on frequently used words with strong visual clues and labels introducing and reinforcing vocabulary.
Discover who’s the King of the Arctic and what life’s really like for penguins with DK Reader Frozen Worlds, packed with facts kids love!

Blowfish’s Oceanopedia: 291 Extraordinary Things You Didn’t Know About the Sea by Tom ‘The Blowfish’ Hird

English | November 2nd, 2017 | ASIN: B073QCTJJD, ISBN: 1786492407 | 250 Pages | EPUB | 10.84 MB

The seas of our planet cover more than seventy percent of the Earth, yet we know less about the ocean depths than the surface of the moon. Join marine biologist and fish-fanatic Tom ‘the Blowfish’ Hird as he lifts the lid on a treasure chest of fascinating facts, to reveal just what we do know about what lurks beneath the waves.

Birdmania: A Remarkable Passion for Birds by Bernd Brunner

English | October 21st, 2017 | ASIN: B074CPKM8B, ISBN: 1771642777 | 207 Pages | EPUB | 44.64 MB

There is no denying that many people are crazy for birds. Packed with intriguing facts and exquisite and rare artwork, Birdmania showcases an eclectic and fascinating selection of bird devotees who would do anything for their feathered friends.
In addition to well-known enthusiasts such as Aristotle, Charles Darwin, and Helen Macdonald, Brunner introduces readers to Karl Russ, the pioneer of “bird rooms”, who had difficulty renting lodgings when landlords realized who he was; George Lupton, a wealthy Yorkshire lawyer, who commissioned the theft of uniquely patterned eggs every year for twenty years from the same unfortunate female guillemot who never had a chance to raise a chick; George Archibald, who performed mating dances for an endangered whooping crane called Tex to encourage her to lay; and Mervyn Shorthouse, who posed as a wheelchair-bound invalid to steal an estimated ten thousand eggs from the Natural History Museum in Tring.
As this book illustrates, people who love birds, whether they are amateurs or professionals, are as captivating and varied as the birds that give flight to their dreams.