CCEA GCSE Biology, Third Edition

Biology and Genetics

Denmour Boyd, James Napier, “CCEA GCSE Biology, Third Edition”
Novel Chemical Tools to Study Ion Channel Biology (Advances in Experimental Medicine and Biology) by Christopher Ahern
Necrotic Cell Death (Cell Death in Biology and Diseases) by Han-Ming Shen
Biochemical Basis and Therapeutic Implications of Angiogenesis, Second Edition By Jawahar L. Mehta, Pankaj Mathur, Naranjan S. Dhalla
RNA Activation (Advances in Experimental Medicine and Biology) by Long-Cheng Li

Denmour Boyd, James Napier, “CCEA GCSE Biology, Third Edition”

English | ISBN: 1471892158 | 2017 | EPUB | 176 pages | 15 MB

Build your students’ scientific thinking and practical skills with this Third Edition textbook, developed specifically for the 2017 GCSE specifications, from the No. 1 publisher for CCEA GCSE Science.- Develop understanding with clear Examples, Tips and Practical activities.- Prepare students for assessment with Test Yourself questions, Maths practice and Exam-style questions throughout. – Provides everything you need for GCSE Biology and the Biology content of GCSE Double Award Science.- Supports Foundation and Higher-tier students in one book.

Novel Chemical Tools to Study Ion Channel Biology (Advances in Experimental Medicine and Biology) by Christopher Ahern

English | 3 Oct. 2015 | ISBN: 1493928449 | 164 Pages | PDF | 5.58 MB

This volume describes chemical approaches to assess ion channel structure, function and pharmacology. Topics discussed include the use of engineered ionizable side chains to obtain information on permeation pathways and the local environment; the modification of engineered cysteine side chains, including cysteine scanning mutagenesis and the attachment of fluorescent probes and bio-reactive tethers; and the nascent use of genetic code expansion, evaluating its applications to ion channel and membrane proteins. This comprehensive text provides multifaceted perspectives on the great diversity of state-of-the-art methods which take advantage of the ever-expanding chemical toolbox to study ion channel biology.
Capturing the contributions and innovations of renowned laboratory researchers in transmembrane protein study for the first time, this book is comprehensive in scope. It covers a wide array of experimental approaches: photochemistry, novel biological tools, and innovative spectroscopy, all combined with traditional techniques of electrophysiology and molecular biology. Novel Chemical Tools to Study Ion Channel Biology, part of the bestselling Advances in Experimental Medicine and Biology series is ideal for researchers and advanced students interested in biochemistry, biophysics, fluorometry, electrophysiology, and chemical biology.

Necrotic Cell Death (Cell Death in Biology and Diseases) by Han-Ming Shen

English | 29 Mar. 2014 | ISBN: 1461482194 | 412 Pages | PDF | 7.6 MB

Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis. This book presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. ​In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive “death machinery” in response to various stimuli like oxidative stress or DNA damage.

Biochemical Basis and Therapeutic Implications of Angiogenesis, Second Edition By Jawahar L. Mehta, Pankaj Mathur, Naranjan S. Dhalla

English | PDF | 2017 | 542 Pages | ISBN : 3319611143 | 10.35 MB

This book covers the latest developments in the therapeutic implications of angiogenesis, ranging from angiogenesis in the brain, angiogenesis in cancer, angiogenesis’ role in atherosclerosis and heart disease as well as metabolic disorders and peripheral vascular disease.
The book is comprehensive in its coverage of angiogenesis in a diverse set of diseases and examines the role of cellular and subcellular structures during the development of angiogenesis. Well-organized and thorough, this is an ideal book for researchers and biomedical engineers working in the field of therapeutic implications of angiogenesis.

RNA Activation (Advances in Experimental Medicine and Biology) by Long-Cheng Li

English | 3 July 2017 | ISBN: 9811043094 | 239 Pages | EPUB | 2.67 MB

This book offers an essential guide to RNA activation (RNAa), an emerging and fascinating new field. RNAa is a small RNA-guided and Argonaute-dependent gene regulation phenomenon in which promoter-targeted short double-stranded RNAs (dsRNAs) induce target gene expression at the transcriptional level. It occurs primarily in the nucleus and can be mediated by artificially designed short duplex RNAs that target regulatory sequences (e.g., promoters, genes’ 3’ termini and enhancers) and naturally occurring small RNAs (e.g., miRNAs and C. elegans 22G-RNAs).
With contributions from internationally respected RNA experts, this book provides comprehensive coverage of different RNAa mechanisms and a timely update on recent advances in RNAa research, with a focus on developing RNAa-based therapeutics. Special chapters are also devoted to the topics of gene activation induced by antisense oligonucleotides and the CRISPR system. As the first book to cover RNAa, it will be of interest to a wide audience, from scientists in academia and the pharmaceutical industry to clinicians who wish to further explore the biology of RNAa and related phenomena, so as to harness their full potential for use in biotechnology and drug development.